The IVF Journey with Dr Michael Chapman
The IVF Journey with Dr Michael Chapman is a podcast that guides listeners through the process of in vitro fertilization and fertility treatment. Dr Michael Chapman, a prominent Australian fertility specialist, shares expert insights, medical advice, and emotional support for individuals and couples pursuing parenthood. Each episode aims to demystify IVF, covering topics from diagnosis to treatment options, while offering hope and practical guidance along the path to having a baby.
Episodes
576. Lifestyle, Scar Tissue, and Failed Fertilisation: Your Questions Answered
In this episode, Prof Chapman answers listener questions on what couples can do to improve their chances of a healthy pregnancy, and why the basics of not smoking, moderate drinking and a healthy weight matter far more than trendy diets or supplements. He explains Asherman’s syndrome, how scarring of the uterine cavity can prevent implantation, how often it occurs after a D&C, and why a hyste
575. Is It the Egg, the Sperm or the Lab: The Truth About Fragmenting Embryos
In this episode, Prof Chapman explains what it means when embryos repeatedly fragment across multiple IVF cycles, and how to work out whether the cause lies with the lab, the sperm or the egg. He shares how the timing of fragmentation can point towards sperm DNA issues, why egg quality is the more common culprit even in younger women, and how a specialised polarised light technique lets his team l
574. Embryo Grading Explained: Does an AA Really Beat a BB
In this episode, Prof Chapman explains how embryologists grade a day five blastocyst and what those numbers and letters actually mean for your chances of pregnancy. He walks through the development scale from one to five, the A to D grades for the inner cell mass that becomes the baby and the outer layer that forms the placenta, and why the gap between an AA and a BB is only a few percentage point
573. Endometriosis Before Pregnancy: The Tests You Should Consider
In this episode, Prof Chapman answers a listener’s question about trying for a baby with endometriosis. He explains that while the condition is being diagnosed more often, most women with endometriosis still go on to conceive, though the stage of the disease matters. He walks through the assessments worth considering, from a detailed specialist ultrasound and laparoscopy to checking that the
572. Inside the Lab: How Scientists Give Your Eggs the Best Chance
In this episode, Prof Chapman takes you inside the IVF laboratory to follow the journey from egg to embryo. He explains why stimulation aims for multiple eggs, how scientists recognise a mature egg, and why egg quality can decline with age. He also covers the two ways eggs are fertilised, conventional IVF and ICSI, what to expect from that next-morning phone call, and how time-lapse incubators hav
571. Does Stopping Ozempic Affect Your IVF Cycle
In this episode, Prof Chapman answers a listener question from Mary, who asks whether stopping Ozempic six weeks before an IVF cycle could affect the outcome. He explains that while drug companies remain cautious for now, no abnormalities have been detected in the many pregnancies occurring in women using these medications. In fact, because obesity can impair fertility, the weight loss these drugs
570. The Truth About Steroids and IVF Add-Ons
In this episode, Prof Chapman unpacks the science behind immune add-ons in IVF, explaining why an embryo behaves almost like a transplant and how a woman’s body has to tolerate a pregnancy that is half foreign. Responding to a listener’s question about steroids, NK cells and CRP, he separates the one immunological condition backed by real evidence, antiphospholipid syndrome, from the m
569. How Many Eggs Do You Really Need? The Science of Your IVF Cycle
In this episode, Prof Chapman unpacks the science behind IVF stimulation protocols and why they sit at the heart of a fertility specialist’s skill. He explains how the short antagonist cycle became the standard for around 95% of Australian cycles, why it has largely replaced the older long protocol, and how it lowers the risk of ovarian hyperstimulation. He also breaks down how your doctor d
568. Varicocele Repair or Straight to IVF: What the Evidence Really Says
In this episode, Prof Chapman unpacks one of the more contested questions in male fertility, whether to surgically repair a varicocele or move directly to IVF. He explains why these varicose veins around the testicle may quietly warm it beyond its optimal temperature and dampen sperm production, and why the evidence for fixing them is far more borderline than many assume. Drawing on decades of res
567. Your Fertility Questions Answered: PMOS Myth and Endometriosis Before IVF
In this episode, Prof Chapman answers two listener questions that cut to the heart of some common fertility confusion. First, does the pill cause PCOS? The short answer is no, but the fuller story is more interesting, including why scientists may soon be renaming the condition PMOS, and how coming off the pill can unmask irregular periods that were there all along. Prof Chapman then turns to a lis
566. Extended Carrier Screening Explained: Preventing Rare Childhood Diseases
In this episode, Prof Chapman unpacks extended carrier screening, the test that helps prevent some of the rarest and most serious childhood diseases before a baby is even conceived. He explains how we all carry genetic mutations without knowing it, in fact 98% of us do, and why they only become a problem when both partners happen to share the same one. Prof Chapman walks through the three most com
565. Why 95% of IVF Patients Don’t Need Mental Health Screening
In this episode, Prof Chapman tackles a question many patients wonder about but rarely ask: should depression and anxiety screening be standard before starting IVF? His answer is a firm no, and he explains why, drawing on the history of mandatory counselling in Victoria that was eventually abandoned because 95% of patients simply didn’t need it. But that doesn’t mean the emotional side
564. Banking Time: Why Freezing Eggs Now Buys You Options Later
In this episode, Prof Chapman unpacks the reality behind delayed parenthood, a trend driven by both partners as often as by women alone. He explains how the odds of conceiving within a year fall from around 90% at 35 to roughly 60% by 40, and why declining egg quality and numbers sit at the heart of that shift. He walks through egg freezing as a hedge against the ticking clock, noting that 30 to 3
563. The Truth After Four Miscarriages: Still 60-70%
In this episode, Prof Chapman cuts through the tests and treatments marketed to women after recurrent miscarriage and asks a simple question: where’s the evidence? He unpacks the $1,500 endometrial receptivity test shown to have no benefit, the pivot to microbiome testing, and immune treatments sold without solid proof — while separating what’s genuinely useful from what he calls ̶
562. What the Evidence Really Says About Miscarriage Prevention
In this episode, Prof Chapman takes a hard look at the growing menu of tests and treatments marketed to women after recurrent miscarriage — and asks a simple question: where’s the evidence? He unpacks the $1,500 endometrial receptivity test that took eight years and a gold-standard trial to show no benefit, the same company’s pivot to uterine microbiome testing, and the murky world of
561. Recurring Miscarriage,Egg Freezing, and the IVF Cliff
In this episode, Prof Chapman tackles one of the most heartbreaking questions in fertility, why miscarriages keep happening. Responding to a listener who has faced four losses across natural and IVF conceptions, he walks through the biggest culprit, genetic abnormalities in the embryo, and explains why age and egg quality sit at the centre of it all. He unpacks the other hidden causes worth invest
560. Egg Quality, Chromosomes, and the Race Against Time
In this episode, Prof Chapman unpacks what specialists actually mean when they talk about egg quality. He explains that quality comes down to an egg’s competency to fertilise and produce an embryo with the right number of chromosomes, and why that process becomes less reliable as women age. He describes the tiny energy-producing structures called mitochondria, the batteries inside every egg,
559. The Egg Countdown: Why Age is Fertility’s Biggest Factor
In this episode, Prof Chapman explains one of fertility’s biggest puzzles: why a woman’s biological clock runs down so much faster than the rest of her body. Drawing on decades of experience and more than three and a half thousand babies, he walks through the remarkable journey of your eggs, from the millions laid down before you were even born, to the half a million you had at birth,
558. PCOS Is Now PMOS. Here’s What Changed
In this episode, Prof Chapman and fertility nurse Natalie tackle one of the most-asked questions on the YouTube channel: the recent renaming of PCOS to PMOS. Prof Chapman explains how the change came out of a roomful of specialists, each with their own stake in the name, and why he sees it as a positive move, not least because so many patients hear “cysts on the ovary” and immediately
557. Over 40 and Repeating IVF Cycles: Get a Second Opinion First
In this episode, Prof Chapman is joined by fertility nurse Natalie to answer one of the most common questions from listeners: what should you do when you’re in your 40s and cycle after cycle isn’t working? Natalie explains why going back to basics matters — reviewing your initial workup, checking whether tests like AMH and antral follicle counts need repeating, and looking at inflammat
556. IVF Breakthrough: What’s Actually Coming Next
In this episode, Prof Chapman answers a listener question about the future of IVF, covering what innovations are genuinely exciting and whether treatment will become more accessible and affordable. He reflects on how success rates have climbed from 10% to around 40% per embryo transfer over three decades, and gives his honest take on the current “flavours of the month”: AI in embryo se
555.Beyond the Cycle: The Support IVF Patients Are Missing
In this episode, Prof Chapman sits down with fertility nurse Natalie to talk about the moments IVF patients often face alone — the late-night bleeding scare, the anxious wait after a positive test, the questions that come up between appointments. They discuss why a positive pregnancy test isn’t the finish line, the reassurance of regular early-pregnancy monitoring through to 10 weeks, and ho
544. The Failed Cycle Conversation Every IVF Patient Needs
In this episode, Prof Chapman is joined by a fertility nurse to unpack what should happen after a failed IVF cycle — and why so many patients are left without answers. They explore the emotional fallout of a negative pregnancy test, the delays patients face in getting support from busy clinics, and the value of having someone who can genuinely listen between appointments. Prof Chapman also shares
553. Your First IVF Injection: Who Do You Call When You’re Not Sure
In this episode, Prof Chapman is joined by a fertility support nurse to explore the gaps in patient care during IVF treatment. They discuss the most common concerns women face — from needle phobia and administering that first injection, to post-egg-collection bleeding and knowing when symptoms warrant escalation. Prof Chapman offers a frank comparison of Australia’s premium versus low-cost I
522. This is Why 60% of IVF Patients Fail on Their First Cycle
Prof. Chapman introduces Natalie from Australia IVF Concierge, highlighting the emotional and practical support gap patients face at home during fertility treatment. Focus: the psychological burden of IVF (60% first-cycle failure rate), medication management, injection anxiety, and waiting uncertainty. Natalie explains how nurse-led home visits provide reassurance, education, and holistic support
551. The Truth About Ovarian Tissue Freezing and IVF Pregnancy Monitoring
In this episode, Prof Chapman explains ovarian tissue cryopreservation, including who it is genuinely suitable for, why it remains largely an experimental fertility preservation technique, and its role for women facing urgent cancer treatment.
He also answers a detailed question from a patient who has received a strong positive beta hCG result following embryo transfer. Prof Chapman discusses whet
550. Can a Different IVF Protocol Improve Your Chances of Success
In this episode, Prof Chapman explains how he approaches patients who have already spent tens of thousands of dollars on unsuccessful IVF treatment and are seeking a second opinion. He discusses the importance of reviewing previous cycles in detail, identifying anything that may have been missed, and tailoring a new treatment strategy to improve outcomes. Prof Chapman also highlights the often-ove
549. Beyond Success Rates: How to Find a High-Quality IVF Clinic
In this episode, Prof Chapman answers a listener’s question about the success rates of IUI and IVF for a 37-year-old woman, explaining when IUI may be worth trying, why success rates drop after a few cycles, and how IVF can offer significantly higher cumulative pregnancy rates. He also shares practical advice on choosing the right fertility clinic, including what to look for in specialists, labora
548. IVF Ethics: What Really Worries Fertility Experts Today
In this episode, Prof Chapman explores how ethical concerns around IVF have evolved over the past four decades. He reflects on the early fears surrounding IVF, including concerns about interfering with nature and the long-term health of IVF-conceived children, and explains how decades of research have helped address many of those worries. Prof Chapman also shares his views on topics such as gender
547. Frozen Embryos and PGT: Understanding the Risks and Benefits
In this episode, Prof Chapman answers a listener’s question about whether frozen embryos should be thawed, genetically tested, and refrozen for PGT. He explains the small risk of embryo loss associated with the process, how PGT can significantly improve the chances of selecting a genetically normal embryo, and why the decision often depends on age, embryo numbers, and individual fertility goals. P
546. The Truth About Fertility Expectations Nobody Talks About
In this episode, Prof Chapman explains why human fertility is far less predictable than most people expect — and why even healthy couples may need up to 12 months to conceive naturally. He breaks down the real monthly chances of pregnancy, why IVF isn’t always the first answer, and the importance of patience when trying for a baby.
Prof Chapman also shares a serious warning about anabolic steroids
545. How Fertility Specialists Decide Between IUI and IVF
In this episode, Prof Chapman explains how fertility specialists help couples decide between continuing to try naturally, moving to IUI, or starting IVF — without losing valuable time. He breaks down how age, fertility history, success rates, costs, and previous pelvic surgeries all influence treatment decisions. The discussion also covers IVF after endometriosis surgery, ectopic pregnancy, fibroi
544.The Hidden Role of Mitochondria in IVF and Egg Competence
In this episode, Prof Chapman explains the critical role mitochondrial health and energy metabolism play in egg competence and embryo development. He breaks down why egg quality declines with age, how chromosome errors happen, and the science behind popular fertility supplements like CoQ10, NADH, and DHEA. Prof Chapman also discusses emerging treatments such as PRP ovarian rejuvenation, why many t
543. What Fertility Specialist Look After a Failed IVF Attempt
In this episode, Prof Chapman explains how he approaches patients seeking a second opinion after a disappointing IVF experience at another clinic. He discusses the emotional toll of failed fertility treatment, the importance of reviewing previous cycles in detail, and why individualized treatment strategies can sometimes make a difference. Prof Chapman also shares the realities of IVF success rate
542. IVF Strategy for Low Egg Count: Less Can Sometimes Be More
In this episode, Prof Chapman answers a common and important question from patients with low ovarian response: is it worth doing two IVF stimulation cycles close together to improve results? He explains why current evidence doesn’t strongly support repeated or back-to-back stimulation as a way to boost egg numbers, and highlights the role of natural biological variation from cycle to cycle—especia
541. AMH, Egg Quality, and IVF Decisions: What Really Matters for Fertility
In this episode, Prof Chapman explains how AMH levels and antral follicle counts are used to assess ovarian reserve—and why they don’t tell the full story about egg quality or natural conception chances. He clarifies common misconceptions, especially for women trying to conceive in their 30s and 40s, and shares when it may be time to consider IVF. Prof Chapman also discusses the growing role of AI
540. Ovarian Reserved Explained: What AMH Really Means for Your Fertility
In this episode, Prof Chapman explains ovarian reserve, how AMH testing works, and why low levels don’t always mean poor fertility. He highlights that egg quality depends on age—not AMH—and cautions against rushing into IVF based on misunderstood results.
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539. Fibroids & Fertility: What Really Matters for IVF Success
In this episode, Prof Chapman breaks down the facts about fibroids—what they are, why they form, and how they impact fertility. He explains the different types of fibroids based on their location, highlighting why submucosal fibroids are the most significant when it comes to implantation and miscarriage risk. Prof Chapman also walks through how fibroids are diagnosed, when treatment is necessary,
538. Starting IVF Right: Tests, Mosaic Embryos, & Transfer Choices Explained
In this episode, Prof Chapman answers key questions from patients navigating their fertility journey—from what tests to take before starting IVF to how to interpret mosaic embryo results. He breaks down the science behind embryo genetics in simple terms, offering clarity on what mosaic embryos really mean and why they may not be as concerning as they seem. The discussion also explores when fresh v
537. Repeated IVF Transfer Failures: What to Test Before Your Next FET
In this episode, Prof Chapman addresses a challenging case of repeated frozen embryo transfer (FET) failures and explores what truly matters before trying again. He discusses why immune therapies like steroids and Clexane may not be as effective as commonly believed, and highlights the importance of embryo quality—particularly genetic testing to rule out aneuploidy. Prof Chapman also shares emergi
536. Secondary Infertility, Chromosome Testing, & The Egg Quality Myth: What IVF Patients Get Wrong
In this episode, Prof Chapman cuts through common misconceptions in fertility treatment explaining why a previous natural pregnancy doesn’t change the diagnostic process, what “euploid” and “aneuploid” embryos actually mean for IVF success, and why the popular belief that quality always trumps quantity when it comes to eggs is more nuanced than most patients realise.
535. Recurrent Miscarriage Explained: Which Tests Matter and What Actually Helps
In this episode, Prof Chapman breaks down recurrent miscarriage, including which baseline tests are truly worth doing, which findings actually change treatment, and which commonly suggested tests have weak evidence behind them. He explains the role of embryo chromosomal abnormalities, balanced translocation, uterine assessment, antiphospholipid syndrome, sperm DNA fragmentation, and when options l
534. Why IVF Cycles Can Vary So Much — From Trigger Shots to Ovarian Response
In this episode, Prof Chapman answers two important IVF questions: whether an Ovidrel trigger can cause a rise in TSH, and why the same patient can have very different ovarian responses in back-to-back IVF cycles. He explains the biology behind temporary thyroid changes during treatment, the role of rising estrogen, and why ovarian response is never exactly the same from one cycle to the next. Pro
533. Endometriosis and IVF: Why Embryo Freezing Before Surgery Can Protect Your Fertility
In this episode, Prof Chapman explains why severe endometriosis can create a difficult fertility dilemma, especially when ovarian cysts need surgical removal. He shares how surgery for endometriomas, while sometimes necessary, can reduce ovarian reserve by damaging healthy ovarian tissue. Prof Chapman discusses why many fertility specialists now recommend doing IVF first, freezing embryos before s
532. The Hidden Cause of Infertility Most Women Don’t Know They Have
In this episode, Prof Chapman breaks down why endometriosis is one of the most underdiagnosed causes of infertility — affecting up to 30% of infertile women, often with no symptoms at all. He explains exactly how it damages fertility, what to watch for, and why getting the right diagnosis early can make all the difference.
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531. What’s Really Driving IVF Success? Lab Secrets, Frozen Embryos, and Weight Loss Drugs Explained
In this episode, Prof Chapman cuts through the noise to reveal what’s truly moved the needle in IVF over the past decade — and it’s not what most patients expect. From the quiet revolution happening in fertility lab culture mediums and incubators, to the game-changing shift in embryo freezing techniques, Prof Chapman shares the under-the-radar advances that have pushed pregnancy rates
530. Choosing The Right IVF Specialist: Why Expertise Counts
In this episode, Prof Chapman explains why selecting the right fertility specialist can significantly influence your IVF journey and outcomes. Responding to questions about failed protocols, limited embryos in storage, and embryo grading, he breaks down what classifications like “3BB” really mean and how treatment strategies can be refined to improve your chances. Drawing on over four decades of e
529.The Science and Uncertainty of IVF Success Rates
In this episode, Prof Chapman answers a listener’s question about recovering from surgery before restarting IVF, and then opens up about one of the most challenging parts of his work which is the difficult conversations that follow failed embryo transfers.
He explains why even in women under 38, the success rate per transfer is only around 40%, and why that still leaves so many patients searching
528. From Unexplained Infertility to IVF: Choosing the Right Next Step
In this episode, Prof Chapman walks through the clinical pathway for couples diagnosed with unexplained infertility. He explains tubal testing, the temporary fertility boost after flushing the tubes, when to keep trying naturally, and when to move forward to IUI or IVF. Clear, step-by-step guidance to help you feel confident about your next move.
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527. The Real Cost of IVF: What You’re Paying For and Why It Matters
In this episode, Prof Chapman breaks down one of the most common and confronting questions patients ask: “How much is IVF really going to cost?” He explains why IVF prices vary so widely across Australia, unpacking the difference between low-cost and premium services, and what those differences mean for patient care, laboratory standards, genetic testing, staffing, and outcomes. Prof Chapman also
526. Poor Fertilization in IVF: What’s Really Going On?
In this episode, Prof Chapman explains what poor fertilisation means in IVF and why it happens, despite everything appearing “normal.” He walks through expected fertilisation rates, how labs rule out technical issues, and why egg quality, age, sperm health, and DNA fragmentation are the most common underlying factors. Prof Chapman also outlines practical adjustments for future cycles, including th
524. When IVF Gets Hard: Embryos, Emotional Burnout, and Expert Care
In this episode, Prof Chapman explains why there is currently no proven treatment that can reliably increase egg numbers or embryo yield in an IVF cycle, despite bold claims about supplements and therapies. He unpacks the limits of current science, addresses popular compounds like NMN, and emphasizes why lifestyle factors, realistic expectations, expert care, and emotional support matter far more
523. IVF Myths: Vitamins, Supplements, and the Reality of Donor Eggs & Sperms
In this episode, Prof Chapman explains why a healthy diet and folic acid matter and why most advertised supplements don’t improve egg or sperm quality despite bold claims online. He also discusses when donor sperm or donor eggs become a practical next step in fertility treatment, outlining the medical realities, key decision points, and how specialists support patients through what can be an emot
522.Immune Testing in IVF: When Results Don’t Improve Success
In this episode, Prof Chapman explains why extensive immune testing in IVF almost always finds something “abnormal” and why that doesn’t mean treatment will help. He breaks down the science behind immune markers, the lack of proven benefit from immune therapies, and how patients can be misled by results that sound concerning but change nothing clinically.
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521. The Science Behind IVF Add-Ons: Separating Evidence from Assumption
In this episode, Prof Chapman draws on nearly 40 years of IVF experience to unpack the growing use of so-called IVF “add-ons” or adjuvants. He explains why many treatments offered after failed cycles—such as CoQ10, DHEA, and testosterone—are not supported by strong scientific evidence, despite their popularity. Prof Chapman also clarifies real IVF success rates over multiple cycles, challenges mis
520.IVF and Endometriosis: When Surgery Helps, When It Harms, and How to Protect Your Eggs
In this episode, Prof Chapman explains when surgery for endometriosis can improve IVF success and when it may risk reducing ovarian reserve. He unpacks the differences between mild and severe disease, why embryos are often created and frozen before surgery, and how adenomyosis, fibroids, and polyps can affect implantation and miscarriage risk. Prof Chapman also addresses common myths around IVF me
519. Understanding IVF Protocols for Women with PCOS
In this episode, Prof Chapman explains how IVF protocols are adjusted for women with PCOS, why PCOS patients often respond well to IVF, and how modern stimulation and antagonist protocols have significantly reduced the risks of OHSS. He also discusses when it’s worth optimizing health before treatment, why many women with PCOS may not need IVF at all, and what makes embryo transfers slightly more
518. Frozen vs Fresh Embryo Transfer: What the Evidence Really Shows
In this episode, Prof Chapman explains how advances in embryo freezing—particularly vitrification—have transformed IVF outcomes, making frozen embryo transfers just as successful as fresh transfers in many cases. He walks through the pros and cons of fresh versus frozen cycles, the original and current reasons for “freeze-all” strategies, and why factors like hormone levels, uterine environment, O
517. Implantation Failure In IVF: Why It Happens Even If You’re Healthy
In this episode, Prof Chapman explains why implantation failure can happen even in “healthy” patients—starting with the reality that it’s common in nature too. He shares that embryo genetics are a major cause, why PGT can improve success per transfer, and what doctors check next in repeat failures (uterine shape issues, chronic endometritis, key blood tests, and certain medical conditions). He als
516.Endomentrial Receptivity and IVF Timing
In this episode, Prof Chapman unpacks the science behind endometrial receptivity—how the uterine lining changes after ovulation, what the “window of implantation” really means, and why timing is only one piece of the puzzle. He explains how tests like the ERA work, why a large trial found no improvement in pregnancy rates despite the cost, and why results can vary from one cycle to the next. Prof
515. DHEA Supplement in IVF: Helpful Boost or Overhyped Trend?
In this episode, Prof Chapman unpacks the science — and the uncertainty — surrounding DHEA supplements in IVF. He explains what DHEA actually does, why androgens matter for egg development, and why older women may consider it despite mixed evidence. With practical insights, clinical experience, and a candid look at the research, he offers clear guidance on when DHEA might help, when it likely won’
514.Embryo Selection Tools: What Works, What Doesn’t, and Why Regulation Matters
In this episode, Prof Chapman unpacks the science behind embryo selection—what truly improves outcomes, what’s more hype than help, and why some tools may need pharmaceutical-level regulation. He explains how genetic testing compares to AI-driven selection, why non-invasive methods still fall short, and the critical role of trained embryologists in guiding success. This conversation offers a clear
513. Why Personalized IVF Treatment Matters: Insights From Prof Michael Chapman
In this episode, Prof Chapman breaks down what personalized medicine truly means in the world of fertility care. He explains why tailored treatment—not “one-size-fits-all” protocols—is essential for giving patients the best chance of success. From thorough history-taking and detailed diagnostic tests, to choosing the right medications, addressing conditions like endometriosis, and avoiding unneces
512. Why Genetic Testing Is Transforming IVF Success Rates — Even for Women in Their 40s
In this episode, Prof Chapman explains how modern genetic testing of embryos is dramatically improving IVF outcomes, even for patients in their mid-40s. He shares two remarkable recent cases of 44-year-old women who each produced a single embryo—both genetically normal—leading to unexpectedly high chances of pregnancy.
Prof Chapman also breaks down the evolving science behind embryo screening, why
511. Pre-implantation Genetic Testing: Boosting Success Rates and Reducing IVF Stress
In this episode, Prof Chapman explains how embryo genetic testing has evolved over 25 years—from basic chromosome counting to today’s highly accurate methods—and what that means for IVF success rates. He breaks down the true benefits, the financial considerations, the challenges posed by mosaic embryos, and why age plays such a crucial role in deciding whether testing is worthwhile.
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510. Modern Treatments for Male Infertility: From Hormone Therapy to ICSI
In this episode, Prof Chapman explores how modern medicine approaches male infertility—from identifying when genetic limitations make treatment impossible, to boosting hormone signals with medications like Clomiphene, to using direct testicular stimulation. He also explains surgical sperm retrieval for men with no sperm in the ejaculate and highlights how ICSI has transformed outcomes, allowing ev
509. Understanding Male Infertility: How Size, Veins, and Temperature Impact Sperm
In this episode, Prof Chapman breaks down the key investigations behind male infertility—from assessing testicular size to detecting varicose veins and understanding why temperature plays such a crucial role in healthy sperm production. He also explains how ultrasounds, hormone tests, and genetic screening help pinpoint the root causes and guide the next steps toward effective treatment.
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508. Understanding Male Infertility: What Really Drives Male Reproductive Health
In this episode, Prof Chapman breaks down how sperm are made—using a relatable “factory floor” analogy to explain the 90-day production process, the brain’s role as the “foreman,” and the key hormones that signal healthy spermatogenesis. He also highlights common disruptors such as stress, tumors, and especially gym supplements that can shut down sperm production in men under 30. A clear, practica
507.Understanding Male Infertility: Breaking the Myths and Finding Hope (Part 1)
In this episode, Prof Chapman discusses the often-overlooked topic of male infertility — a challenge that affects many couples but is rarely addressed with the sensitivity it deserves. He explores the psychological impact on men, debunks common myths about sperm count and masculinity, and explains what sperm quality really means. From understanding sperm concentration, motility, and morphology to
506. Inside the Lab: How Science Is Shaping the Next Decade of IVF
In this episode, Prof Chapman unpacks the real science behind artificial wombs and lab-grown eggs — and why these breakthroughs are still years away from mainstream fertility clinics. He also discusses when pre-genetic testing truly makes sense, who benefits most, and how it helps couples avoid the heartbreak of failed cycles and miscarriages.
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505. Inside the Egg: What Affects Quality—and What You Can (and Can’t) Change
In this episode, Prof Chapman unpacks one of the most common fertility questions: “What can I take to improve my egg quality?” He shares the hard truth about lifestyle factors, the limits of supplements, and why scientific evidence still lags behind online claims. From DHEAS to CoQ10, Prof Chapman separates hopeful theory from proven fact—offering clear guidance for anyone navigating fertility tre
504. The Breakthrough that Changed Everything: How ICSI Transformed Male Infertility
In this episode, Prof Chapman reflects on the most remarkable breakthrough in his decades-long career — the introduction of intracytoplasmic sperm injection (ICSI) in the early 1990s. He explains how this single innovation revolutionised treatment for men with low or even absent sperm counts, making fatherhood possible where it once seemed impossible. Prof Chapman also traces the evolution of IVF
503. When IVF Doesn’t Work: Next Steps, Success Rates, and Support Options
In this episode, Prof Chapman talks about what happens when IVF doesn’t work — from understanding the reasons behind failed cycles to exploring next-step options like egg or sperm donation. He also shares his clinic’s success rates for women over 30, how remote and overseas patients can access treatment, and the vital role of counseling and emotional support throughout the IVF journey.
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502. When IVF Fails: Understanding Antiphospholipid Syndrome and When to Seek a Second Opinion
In this episode, Prof Chapman answers a listener’s question about antiphospholipid syndrome (APAS) and how it can affect IVF outcomes. He explains how immune-related conditions increase miscarriage risk, and why treatments like heparin and steroids can improve success rates when properly managed. Prof Chapman also shares valuable insights on what to do after a failed IVF cycle—when to change proto
501. The Real Costs of IVF: What Clinics Don’t Always Tell You
In this episode, Prof Chapman answers viewer Jen’s two big questions about IVF costs — what happens financially if your first cycle fails, and what hidden or unexpected fees to look out for. He explains why most clinics don’t offer discounts for additional cycles, breaks down the true cost structure behind IVF treatments, and shares practical advice on what to ask before you start so you know exac
500. Celebrating 500 Episodes: Understanding Polycystic Ovarian Syndrome (PCOS) and Hope for Natural Conception
In this episode, Prof Chapman marks a remarkable milestone — the 500th episode of his fertility podcast. Reflecting on decades of helping couples conceive, he shares insights into one of the most common yet misunderstood fertility conditions: polycystic ovarian syndrome (PCOS). Prof Chapman explains the hormonal imbalances behind PCOS, how medications like Clomiphene and Letrozole can restore ovul
499. Why Australia Leads the World in IVF – Ethics, Access, and the Future of Fertility
In this episode, Prof Chapman explains why Australia ranks among the top three countries globally for IVF use — not because of higher infertility rates, but because of its unique Medicare support and ethical framework. He discusses how affordability and access have shaped fertility care, the impact of conditions like undescended testicles on sperm health, and the ethical challenges of doctors reco
498. IVF Anywhere: Zoom Consults, Costs, Immune Myths, and Smarter Cycle Tweaks
In this episode, Prof Chapman explains how interstate and even overseas patients can be managed via Zoom right up to the day before egg collection, outlines consult fees ($370 with ~$160 back on Medicare), and notes which Life Fertility doctors provide end-to-end obstetric care in Sydney.
He separates evidence from hype on uterine lining “receptivity” and immune testing—highlighting antiphospholip
497. Egg Quality, Fibroids, and Fertility After 40
In this episode, Prof Chapman dives into some of the most common — and crucial — fertility questions women ask in their 40s. From how many IVF or egg retrieval cycles might be needed for a successful pregnancy, to the impact of fibroids, and whether you can conceive without fallopian tubes, he breaks it all down with clarity and compassion. Prof Chapman also explores the truth about egg quality —
496. Egg Freezing: Insurance for Fertility’s Future
In this episode, Prof Chapman unpacks the growing trend of egg freezing and why more women in their 20s and 30s are considering it. He explains how the process works, the role of age in fertility, the realistic chances of success, and what to look for when choosing a clinic. From costs and timing to risks and expectations, this is a clear guide to help women make informed decisions about preservin
