Inside Exercise
Inside Exercise interviews leading researchers in exercise physiology and metabolism about the effects of exercise on health. The discussions are scientifically rigorous yet offer practical strategies for listeners. Host Glenn McConell is an Emeritus Professor with over three decades of exercise metabolism research experience and more than 120 published journal articles. He has also compiled a 17-chapter eBook with world experts on exercise metabolism.
Episodes
#90 - Former WR marathoner Derek Clayton with the top researchers who've studied him over 50 years
Dr Glenn McConell chats with legendary Australian former marathon world record holder and lifelong exerciser Derek Clayton and the three top researchers who have tested him over 50 years. Derek, who is now 82 years old, broke the marathon world record in 1967 running 2:09:36 when the previous record was 2:12:11(!). Then in 1969 he ran 2:08:33 a world record which wasn’t broken until 1981. He then
#89 - Concurrent training with Dr Tommy Lundberg
Dr Glenn McConell chats with Dr Tommy Lundberg from the Karolinska Institute in Stockholm, Sweden. He is an expert on resistance training (RT) and has focussed on the effect of concurrent training on exercise adaptations. That is, does doing concurrent resistance and endurance training affect the responses to resistance and endurance training compared to doing either alone. His research has specif
#88 - Exercise preserves muscle and metabolism during cancer with Dr Lykke Sylow
Dr Glenn McConell chats with Associate Professor Lykke Sylow from The University of Copenhagen. She is a rising star in exercise metabolism and in particular the effect of exercise on cancer. This is the second podcast episode on exercise and cancer (See Professor Kathryn Schmitz episode #9).Remarkably she said that if you are a non-smoker your biggest risk of getting cancer is inactivity. Not cle
#87 - Exercise and sports cardiology with Professor Paul D. Thompson
Dr Glenn McConell chats with Professor Paul D. Thompson who is Chief of Cardiology, Emeritus at Hartford Hospital, Hartford, CT and Professor of Medicine, Emeritus at the University of Connecticut. He has published over 500 peer reviewed journal articles, was a past President of the American College of sports medicine (ACSM) and was a impressively fast marathon runner. This is the third of a serie
#86 - Can changing gait reduce running injuries with Professor Bryan Heiderscheit
Dr Glenn McConell chats with Professor Bryan Heiderscheit from the University of Wisconsin in USA. He is an expert on running injuries. This is the third of a series of podcast episodes on running injuries (See Professor Irene Davis’s and Associate Professor Rasmus Østergaard Nielsen’s episodes). Bryan focuses on overstriding and how increasing the stride rate can reduce overstriding and therefore
#85 - Effect of training load and shoes on running-related injuries with Dr Rasmus Østergaard Nielsen
Dr Glenn McConell chats with Associate Professor Rasmus Østergaard Nielsen from Aarhus University who is an expert on the affect of training load and shoes on running-related injuries. This is the second of a series of podcast episodes on running injuries (See Prof Irene Davis’s episode).
Rasmus went from an overweight gamer to an injured runner to a exercise researcher! His research focuses on
#84 - Effect of shoes and gait on running injuries with Professor Irene Davis
Dr Glenn McConell chats with Professor Irene Davis from the University of South Florida who is a top running injuries researcher and the current president of the American College of Sports Medicine. She makes the argument that we were born to run and have evolved to land on the ball of the foot during running and this reduces impact load compared with landing on the heel. Modern running shoes tend
#83 - Applying Sport Science: Lessons from the Olympics and the NBA with Dr David Martin
Dr Glenn McConell chats with Dr David Martin. David has a remarkable and varied background starting off as a research scientist at the Australian Institute Sport and then National Sports Science Coordinator at Cycling Australia. He then became Director, Performance Research and Development at the Philadelphia 76ers. He is currently Chief Scientist, Director of Performance at Apeiron Life, San Fran
#82 - Heart transplant Ironmen!: Upper limits of performance post heart transplant. Prof Mark Haykowsky, Dwight Kroening and Elmar Sprink
Dr Glenn McConell chats with Professor Mark Haykowsky from the University of Alberta, Canada and remarkable heart transplant recipients Dwight Kroening, Edmonton, Alberta, Canada and Elmar Sprink, Cologne, Germany. Dwight was very fit before a heart defect resulted in his heart transplantation (HT) way back in 1986. Elmar was an endurance athlete who suffered a series of cardiac arrests before his
#81 - Muscle recovery after joint injury with Dr Chris Fry
Dr Glenn McConell chats with Associate Professor Chris Fry from the University of Kentucky, USA. Joint injury causes muscle weakness and atrophy (reductions in muscle size) due to the the inactivity but also separately due to the injury itself. Substances are released from muscle to help repair the joint/bone. Prehab is important before surgery. There can be residual effects long after joint injur
#80 - Epigenetics of exercise adaptation and "muscle memory" with Dr Kevin Murach
Dr Glenn McConell chats with Assistant Professor Kevin Murach who is a rising star from the University of Arkansas, USA. Kevin is an expert on muscle, muscle growth, adaptation to exercise training, “muscle memory”, the regulation of muscle growth and muscle memory and the effect of aging etc. Muscle memory definitely seems real (especially in slow muscle fibers). Looks like epigenetics involved m
#78 - Food, exercise and glucose "spikes": should everyone wear a CGM? Glucose spikes are normal physiology!! With Dr Guess and Prof Little
Dr Glenn McConell chats with Dr Nicola Guess from Oxford University, England and Professor Jonathan Little from the University of British Columbia, Canada. Nicola is a dietitian researcher with many years of expertise including the importance or otherwise of glucose “spikes” or excursions and the pros and cons of continuous glucose monitor use. Jonathan is an expert on exercise metabolism who is c
#79 - Exercise and the brain with Dr Jill Barnes
Dr Glenn McConell chats with Associate Professor from the University of Wisconsin-Madison, USA. Jill is an expert on the brain and exercise. We discussed the effect of acute (one bout) and chronic physical activity/ exercise on cognitive function, brain blood flow (BBF), dementia/Alzheimer’s disease risk and progression etc. A very interesting chat. Twitter: @Barnes_Lab0:00. Introduction and welco
#77 - Exercise and pregnancy with Professor Margie Davenport
Dr Glenn McConell chats with Professor Margie Davenport from the University of Alberta, Canada. She is an expert on exercise and pregnancy. We discussed the effect of pregnancy on the health (including pre-eclampsia and gestational diabetes) and exercise performance of the mother and on the health of the fetus during pregnancy and the offspring after pregnancy. It became very clear that there need
#76 - Creatine in exercise and health with Professor Darren Candow
Dr Glenn McConell chats with Professor Darren Candow from the University of Regina. Saskatchewan, Canada. He is an expert on creatine (Cr) and the effects of creatine supplementation on resistance exercise and other exercise. He is also examining the role of creatine in bone metabolism and cognitive function.Get greater increases in strength than muscle mass when supplement with Cr during resistan
#75 - Physiology of exercise in extreme environments: sex as a biological variable with Dr Nisha Charkoudian
Dr Glenn McConell chats with Associate Professor Nisha Charkoudian from the US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA. She is an expert on the effects of extreme environments on exercise capacity. We talked about dehydration, electrolytes, effects of humid vs dry environments etc. We also discussed the importance of considering sex as a biological variable. T
#74- Are beta2-agonists just asthma treatments or also performance enhancers? With Dr Morten Hostrup
Dr Glenn McConell chats with Associate Professor from the University of Copenhagen, Denmark. He is an expert on the effect of beta2-agonist asthma bronchodilator medications (like Ventolin) on muscle and exercise performance. We talked about what is asthma/exercise induced bronchoconstriction, can you train your lungs?, the increased prevalence of asthma in endurance athletes, can asthma limit aer
#73 - Protein and muscle adaptations to loading and unloading with Professor Luc van Loon
Dr Glenn McConell chats with Professor Luc van Loon from Maastricht University, The Netherlands. He is an expert with a wealth of knowledge on the role of physical activity/exercise and nutrition on muscle adaptation. A lot of his research focuses on protein and protein synthesis. He applies these studies to young healthy individuals, the aged and also has conducted important experiments on peopl
#72 - Tendons: from exercise adaptation to injury and rehabilitation, with Professor Michael Kjær
Dr Glenn McConell chats with Professor Michael Kjær from the Department of Clinical Medicine, Bispebjerg Hospital, the University of Copenhagen, Denmark. He is an expert on tendons and exercise. We chatted about muscle vs musculotendinous junction vs tendon, what structures get injured and why, tendon injuries: mechanisms, prevention, treatment, acute vs chronic/overuse tendon injuries, best to re
#71 - Aging, inactivity, atrophy and exercise with Professor Sue Bodine
Dr Glenn McConell chats with Professor Sue Bodine from the Oklahoma Medical ResearchFoundation, Oklahoma, USA. She is an expert on muscle, in particular muscle atrophy with inactivity/aging. We chatted about how with age muscle size is reduced and this is associated with a reduction in muscle fiber size and also a loss of fast muscle fibers. Resistance training (and perhaps intense endurance exerc
#70 - Sleep, recovery and fatigue in athletes with Professor Shona Halson
Dr Glenn McConell chats with Professor Shona Halson from the Australian Catholic University, Melbourne, Australia. We chatted about how much sleep athletes need compared with how much sleep they actually get. Night sleep vs naps vs total sleep in athletes vs non athletes. The importance of consistency of sleep. Caffeine, sleep and exercise performance. Is overtraining actually a lot less common th
#69 - Should middle-aged men pull on lycra? With Dr Andre La Gerche
Dr Glenn McConell chats with Assoc Prof Andre La Gerche a world leading Sports Cardiologist from St Vincent’s Institute of Medical Research, Melbourne, Australia. Acute exercise for long periods at a high intensity can result in abnormal right ventricle function. In addition, years of long, hard exercise training is associated with increased coronary artery calcium (CAC) levels and atrial fibrilla
#68 - Muscle fiber types revisited with Professor Wim Derave
Dr Glenn McConell chats with Professor Wim Derave from the Ghent University in Belgium. We talked about the different muscle fibres/fiber types in humans and his recent evidence that pure Type 2X muscle fibers may not really exist or maybe only in some sedentary individuals. He also made the point that muscle fiber type info is not used enough in sports contexts. He outlined some non invasive ways
#67 - Limitations to VO2 max with Professor Jose Calbet
Dr Glenn McConell chats with Professor José Calbet from the University of Las Palmas de Gran, Canary Islands, Spain. José has a very strong research record and is a global leader in his field. He has done amazing invasive exercise studies in humans to determine the limiting factor(s) to VO2 max. We talked about what is VO2 max, the factors determining VO2 max, the limits to VO2 max, the effects of
#66 - Exercise and the cardiovascular system with Professor Ylva Hellsten
Dr Glenn McConell chats with Professor Ylva Hellsten from the University of Copenhagen in Denmark. She is an authority on the effect of exercise on blood flow and cardiovascular function. We talked about heart rate before exercise and blood flow and blood pressure during and after exercise. She pointed out that muscle blood flow can increase by 100-fold during exercise! We discussed the effect of
#65 - Interactions between exercise and insulin with Professor Erik Richter
Dr Glenn McConell chats with his great collaborator Professor Erik Richter from the University of Copenhagen in Denmark. Erik is an absolute authority and the godfather of the field of glucose metabolism during exercise and how exercise increases insulin sensitivity in muscle. He was the first to show that contraction can increase muscle glucose uptake without insulin but at the same time exercise
#64 - Blood flow restriction and exercise with Dr Jeremy Loenneke
Dr Glenn McConell chats with Associate Professor Jeremy Loenneke from the University of Mississippi, USA. He is an expert on resistance training and in particular the effect of blood flow restriction (BFR) on muscle hypertrophy and strength. He is finding that you can get similar increases in hypertrophy, and close to similar increases in strength, by conducting low load resistance training with b
#63 - Adipose tissue adaptations to exercise and exercise and antipsychotics with Dr David Wright
Dr Glenn McConell chats with Professor David Wright from the University of British Columbia, Canada. He has undertaken a lot of important work on the effect of exercise on muscle glucose uptake and mitochondria and then has branched out to examine the effect of exercise training on mitochondria in adipose tissue (fat). We discussed his work around that and then talked about an interesting new focu
#62 - Interaction of exercise with muscle circadian clocks with Dr Karyn Esser
Dr Glenn McConell chats with Professor Karyn Esser from the University of Florida, USA. She is an authority on circadian biology. We discuss whether exercise affects muscle circadian clocks and whether muscle clocks affect exercise. What is the best time to exercise and to eat etc. Also the effects of jet lag and shift work and how to best manage these. A very interesting chat. Karyn’s Twitter: @k
#61 - Volume versus intensity with Dr David Bishop
Dr Glenn McConell chats with Professor David Bishop from Victoria University in Melbourne, Australia. He has a broad background in exercise physiology research and has focused for many years on exercise and muscle mitochondria. He finds that low volume, prolonged exercise tends to increase mitochondrial volume more than mitochondrial function while sprint exercise training does the opposite, incre
#60 - Skeletal muscle aging and mitochondria: thinking beyond the powerhouse with Dr Russell Hepple
Dr Glenn McConell chats with Professor Russell Hepple from the University of Florida, USA. He is an expert on muscle mitochondria. We tend to think of the mitochondria as the powerhouse of the cell. As Russ clearly explains there is a lot more going on than only this. It is very important that the inner mitochondrial membrane remains impermeable. However, there are situations such as aging, ische
#59 - The gut microbiome in health and sport with Dr Orla O'Sullivan
Dr Glenn McConell chats with Dr Orla O’Sullivan from the Teagasc Food Research Centre, from Ireland. She is a research expert effect of diet and exercise on the gut microbiome (the types of cells in the gut microbiome based on the DNA measurements). She has looked at the gut microbiota in rugby players, cricketers, ironman and other sports. She emphasized the importance of having a diverse gut mic
#58 - Exercise in the cold: impacts on performance and health with Dr Mike Tipton
Dr Glenn McConell chats with Professor Mike Tipton from University of Portsmouth, England. He is an absolute authority on exercise in extreme environments. We talked initially about his important work examining the causes and prevention of drowning in cold water. Autonomic conflict and triathlon mass starts. We then discussed exercise in the cold and cold adaptations and cross adaptation between
#57 - Gut microbiota and exercise with Dr Edward Chambers
Dr Glenn McConell chats with Dr Edward Chambers from Imperial College London who is an expert on the gut microbiota, exercise and metabolism. He has shown that some fibre can be fermented to short chain fatty acids (SCFA) by gut microbiota which can influence skeletal muscle metabolism. In addition, these SCFA can affect appetite. He has also shown that exercise and/or carbohydrate ingestion redu
#56 - Muscle plasticity, aging and exercise with Dr Benjamin Miller
Dr Glenn McConell chats with Professor Benjamin Miller from the Oklahoma Medical Research Foundation (OMRF) who is an expert on muscle proteostasis /plasticity in response to exercise and aging. He has evidence that muscle atrophy with aging may be due more to increased protein breakdown than reduced protein synthesis. He also has found that the top diabetes drug metformin can impair some of the
#55 - Reactive oxygen species (ROS) and exercise with Dr Carlos Henríquez-Olguín
Dr Glenn McConell chats with Dr Carlos Henríquez-Olguín from The University of Copenhagen, Denmark. Carlos is an up and coming rising star exercise metabolism researcher. He discusses the challenges of doing mechanistic exercise research in Chile and how he ended up moving to the University of Copenhagen. Language challenges etc. He has been doing really ground breaking research on reactive oxygen
#54 - Exercise and immunity with Dr Michael Gleeson
Dr Glenn McConell chats with Emeritus Professor Michael Gleeson from Loughborough University, England. He is the biggest global name with many decades of research examining the effects of exercise and diet on the immune system. Exercise is beneficial for the immune system unless it is undertaken at a very high /elite level. A very interesting chat. Twitter: @profmikegleeson0:00. Introduction/Mich
#53 - Aging, exercise and muscle mitochondrial energetics with Dr Paul Coen
Dr Glenn McConell chats with Dr Paul Cohen from Translational Research Institute for Metabolism and Diabetes, AdventHealth Orlando, Florida, USA. He has a very strong track record of research examining muscle mitochondria in health and disease and in particular the effects of exercise in attenuating the reductions in mitochondrial function with age. A very interesting chat. Twitter: @CoenPM
0:00
#52 - Environmental physiology: results and lessons from the lab vs real life with Dr Lars Nybo
Dr Glenn McConell chats with Professor Lars Nybo from the University of Copenhagen. He is an expert on the effects of environmental conditions on exercise. Here he discussed factors effecting cycling performance and then focused on circumstances where one needs to be careful applying findings from the lab to the real world. A very interesting chat. Twitter: @Nyborger Nybo0:00. Introduction2:20. L
#51 - Maximizing muscle hypertrophy with Dr Brad Schoenfeld
Dr Glenn McConell chats with Professor Brad Schoenfeld from Lehman College, The City University of New York, the Bronx, New York. He has a very strong track record on research examining how to maximize muscle hypertrophy and also important protein synthesis and strength studies. He also applies his knowledge being a former personal trainer and a successful competitive natural body builder. We disc
#50 - Acute catabolic (yes, catabolic...) response of bone to exercise with Dr Wendy Kohrt
Dr Glenn McConell chats with Professor Wendy Kohrt from the University of Colorado Anschutz Medical Campus. She has an extremely strong track record of research on how exercise affects bone. She has changed her thinking of late after finding that acute exercise actually has a catabolic effect on bone even though overall, it can have beneficial effects. This is dependent on the actual exercise/spo
#49 - Remarkable benefits of exercise in myopathy patients with Dr Mark Tarnopolsky
Dr Glenn McConell chats with Professor Mark Tarnopolsky from McMaster University in Canada. Mark has done pioneering studies in many areas including sex differences and exercise, HITT training and creatine supplementation. Today we focus on his remarkable work with muscle myopathies. Exercise can be beneficial in all muscle myopathies in regards to function and/or healthspan and/or lifespan. The
#48 - Dr David Costill: Legend of exercise physiology and human performance
Dr Glenn McConell chats with Emeritus Professor David “Doc” Costill who is an absolute legend of exercise physiology and human performance. He was Founder and Director of the Human Performance Laboratory at Ball State University in Muncie, Indiana, USA. He made the lab one of the top labs in the world and has a remarkable track record. He supervised the who’s who of exercise physiology research i
#47 - Speed-duration relationship across the animal kingdom with Dr Mark Burnley
Dr Glenn McConell chats with Dr Mark Burnley from the Loughborough University in England. He is an expert on critical power (cycling) and critical speed (running). We compared and contrasted the speed duration relationship across the animal kingdom. Mark is an absolute wealth of knowledge on exercise intensity domains and critical power etc and comparative exercise physiology. Critical power is es
#46 - What are we polarizing in polarized endurance training? Dr Stephen Seiler
Dr Glenn McConell chats with Professor Stephen Seiler from the University of Agder in Norway. He is American who started his career in USA before moving to Norway almost 30 years ago. He points out that most exercise training research is based around university semesters with mainly untrained to trained transitions which is very different to what athletes do. Stephen coined the term polarized trai
#45 - From heat shock doc to kettlebells with Dr Pope Moseley
Dr Glenn McConell chats with Professor Pope Moseley from Arizona State University in the United States. Pope has a lung and critical care background. We spoke about his early heat shock protein work with Carl Gisolfi, a giant of research on exercise and the gut. Also heat, heat shock proteins, gut leak and heat stroke, exercise training and gut leak, heat shock proteins and autophagy, “Heat shock
#44 - The science of sports injuries and how to prevent and treat them with Dr Kristian Thorborg
Dr Glenn McConell chats with Professor Kristian Thorborg from the University of Copenhagen in Denmark who also has s position at Lund University in Sweden. We spoke about the role of the placebo effect, sports injury prevention and especially the role of eccentric exercise, plyometrics, whether stretching reduces sports injuries, prehabilitation, exercise to avoid surgery, rehabilitation, is ice u
#43 - The importance of exercise in space with Dr Scott Trappe
Dr Glenn McConell chats with Professor Scott Trappe, Director of the Human performance laboratory at Ball State University, Indiana, USA. We spoke about the influence that Scott’s supervisor, the great David “Doc” Costill, has had on exercise physiology (long time Ball State HPL Director before Scott). We then discussed the negative effects of space on the human body and whether exercise can mini
#42 - Circadian rhythms, exercise and type 2 diabetes with Dr Juleen Zierath
Dr Glenn McConell chats with Professor Juleen Zierath who has had a remarkable background with current senior roles at both the Karolinska Institute in Sweden and the University of Copenhagen in Denmark. She was also previously the Chair of the Nobel Committee. We discuss the effects of circadian rhythms on: muscle insulin sensitivity, metabolic responses to exercise in T2D vs controls, exercise
#41 - Zone 2 training: why all the talk? With Dr Andrew Coggan
Dr Glenn McConell chats for a second time with Associate Professor Andrew Coggan from Indiana University, Purdue University, Indianapolis (IUPUI), USA. Andy was an elite time trial cyclist who has a very impressive research track record. He also wrote the first book on training and racing using power (training levels). As was the case last week with Michael Joyner, Andy makes the case that differe
#40 - The history of endurance training methods with Dr Michael Joyner
Dr Glenn McConell chats for a second time with Professor Michael Joyner from the Mayo Clinic, Minnesota, USA. Michael blew me away with his absolutely amazing knowledge on past athletes and coaches and their endurance training methods. Very different types of training can result in similar results. His running Haiku: Run a lot of miles, some faster than your race pace, rest once in a while. Michae
#39 - Why muscle glycogen is important with Dr Niels Ørtenblad
Dr Glenn McConell chats with Professor Niels Ørtenblad from the University of Southern Denmark. He is an expert on muscle glycogen. We discussed the history of muscle glycogen and exercise research, the effect of diet and exercise training on muscle glycogen levels and use, the distribution and use of muscle glycogen within different muscle fibre compartments, unusual to fully deplete muscle glyc
#39 - Do keto diets and ketone supplements make sense for exercise and health with Dr Jonathan Little
Dr Glenn McConell chats with Professor Jonathan Little from University of British Columbia. Kelowna, Canada. He is an expert on metabolism, nutrition, type two diabetes and exercise. We discussed what are keto (ketogenic) diets, different types of keto diets, the rationale for them and their effect on heath and exercise performance. We then did the same with ketone supplements. Whether there is a
#38 - Harassment, abuse and mental health in athletes with Dr Margo Mountjoy
Dr Glenn McConell chats with Professor Margo Mountjoy from McMaster University in Canada. A wide ranging and at times emotional discussion about the types of harassment and abuse (psychological abuse underlies most), prevalence of abuse (higher in marginalized groups), power relationships, reporting policies and procedures, barriers to reporting abusive behavior, the Nasser case, how empower the g
#37 - Exercise in the heat, dehydration, fluid ingestion and circulation with Dr José González-Alonso
Dr Glenn McConell chats with Professor José González-Alonso from Brunel Univesity London. We discussed exercise in the heat, dehydration, fluid ingestion, blood flow, metabolism and human circulation. He has a very strong research track record having researched these areas for around 35 years. We discuss how he began his career doing research with some very big names.
0:00. Introduction and how J
#36 - Effect of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance with Dr Kirsty Elliott Sale
Dr Glenn McConell chats with Professor Kirsty Elliott-Sale from Manchester Metropolitan University, England. She is an expert on female exercise physiology . We discuss the effects of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance. As will become apparent, more research needs to be done on these important areas.
0:00. Introduction and Kirsty’s intro t
#35 - Gaining muscle to combat losing muscle with Dr Stuart Phillips
Dr Glenn McConell chats with Professor Stuart Phillips from McMaster University in Canada. He is the world expert on protein needs for optimal muscle mass with exercise. We discussed gaining muscle to combat losing muscle. The discussion centered around resistance training, dietary protein needs, whether need protein from meat, the timing of protein intake, the need for protein supplements and pro
#34 - The psychobiology of endurance performance with Dr Samuele Marcora
Dr Glenn McConell chats with Professor Samuele Marcora from the University of Bologna in Italy. He is an expert on the psychobiology of endurance performance and fatigue. We discussed the importance of the perception of effort/rating of perceived exertion on exercise performance and fatigue. Pros and cons of zoning in vs zoning out. How the perception of effort can be modified by factors such as e
#33 - Fat metabolism, insulin resistance and exercise with Dr Graham Holloway
Dr Glenn McConell chats with Professor Graham Holloway from the University of Guelph in Canada. He is an expert on mitochondrial bioenergetics. We discussed the effect of exercise intensity and duration and exercise training on fat/lipid and carbohydrate metabolism, whether alterations in substrate availability such as high fat diets, high fat meals, high carbohydrate meals etc affect fat oxidatio
#32 - Carbohydrate metabolism during exercise with Dr Mark Hargreaves
Dr Glenn McConell chats with Professor Mark Hargreaves from the University of Melbourne in Australia. He is a leader in exercise metabolism/physiology and was Glenn’s PhD supervisor. The discussion centred around the effects of muscle glycogen availability and carbohydrate (CHO) ingestion on exercise metabolism and also performance/fatigue. There was also discussion of high fat/ketogenic die
Inactivity- the imperceived muscle stressor with Dr Paul Greenhaff
Dr Glenn McConell chats with Professor Paul Greenhaff from the University of Nottingham in England. He has been a leader in exercise metabolism research for over 30 years. He was the top global researcher in creatine and exercise for many years. His focus over several years has been on inactivity. We discuss the metabolic effects of inactivity and immobilization on insulin sensitivity and protein
Altitude training and hypoxic conditioning with Dr Grégoire Millet
Dr Glenn McConell chats with Professor Grégoire Millet from the University of Lausanne in Switzerland. He is an absolute world leader in research into altitude training and hypoxic conditioning. This area has progressed greatly from Live High-Train High (LHTH) to Live High-Train Low (LHTL),
LLTH and LHTL (and High). The type of attitude training/hypoxic conditioning one would undertake depends on
Exercise protects and treats fatty liver with Dr John Thyfault
Dr Glenn McConell chats with Professor John Thyfault from the University of Kansas Medical Center. We discuss how when one takes in more calories than they expend, this results in elevated fat and glucose in the blood which disrupts liver metabolism. This can result in fatty liver and insulin resistance. Exercise can prevent and treat fatty liver even independently of body weight. There are import
How does exercise affect metabolism after eating with Dr Javier Gonzalez
Dr Glenn McConell chats with Professor Javier Gonzalez from the University of Bath. We discuss carbohydrate (CHO) metabolism at rest when fasted vs fed, during exercise when fasted vs fed and the effects of exercise on metabolism after a meal. We also discuss muscle and liver glycogen resynthesis and the effects of different types and amounts of carbohydrate. Finally, we touch on Javier’s study wi
Unravelling the mysteries of the vasculature in muscle with Dr Katrien de Bock
Dr Glenn McConell chats with Professor Katrien de Bock from ETH Zürich - Swiss Federal Institute of Technology. We discussed how exercise training increases blood vessels in skeletal muscle. Also muscle cells and blood vessels in regards to injury/repair and cancer. We also discussed exercise and leucine sensitivity.
0:00. Introduction
2:00. What is the vasculature. Blood vessels Endo
Herman's theory that exercise doesn't affect body weight with Dr Herman Pontzer
Dr Glenn McConell chats with Professor Herman Pontzer who is a Human Evolutionary anthropologist from Duke University. Herman has undertaken research with current day hunter gather communities and shown that although they are a lot more physically active than western societies, their average energy expenditures are not higher!! Constrained energy model (energy compensation): that when exercise the
Your parent's diet and exercise affects your health with Dr Laurie Goodyear
Dr Glenn McConell chats with Professor Laurie Goodyear from the Joslin Diabetes Centre at Harvard Medical School. Laurie is a very big name in the field of exercise metabolism with a remarkable track record. She has examined glucose and fat metabolism during exercise and more recently has been focusing on developmental origins of health and disease and the benefits of exercise. Exercise of the mot
Muscle fatigue with Dr Håkan Westerblad
Dr Glenn McConell chats with Professor Håkan Westerblad from the Karolinska Insitute in Sweden. Håkan is a massive name in the field examining the mechanisms of muscle fatigue. The first 20 min is a general discussion of fatigue during exercise which is suitable for a general audience. Then it becomes more complex as as we discuss the mechanisms causing fatigue.
0:00. Introduction
0:5
Muscle injury, repair and aging with Dr Abigail Mackey
Dr Glenn McConell chats with Associate Professor Abigail Mackey from the University of Copenhagen. Abigail is an expert on muscle injury, repair and aging. They discussed these plus the protective effect of repeated bouts of eccentric exercise, whether it’s smart to take anti-inflammatories after injury, different types and areas of injuries, causes of injuries, treatment of muscle injuries,
Exercise and insulin action with Dr Jorgen Wojtaszewski
Dr Glenn McConell chats with Professor Jorgen Wojtaszewski from the University of Copenhagen. Jorgen has an exceptional track record of research examining how exercise increases glucose uptake during the exercise and how exercise increases the sensitivity of muscle to insulin. We discuss insulin resistance, insulin sensitivity, type 1 diabetes and exercise, type 2 diabetes and exercise, glucose up
Relative energy deficiency in sport (RED-S) with Dr Trent Stellingwerff
Dr Glenn McConell chats with Dr Trent Stellingwerff from the Canadian Sport Institute Pacific. Trent has a very interesting background in applied research and translation through coaching Olympic athletes etc. Formerly head of R&D at PowerBar. In a really fun chat we talked mainly about his research with the very important relatively new area of relative energy deficiency in sport (RED-S). RED
The skeptics guide to sports science with Dr Nick Tiller
Dr Glenn McConell chats with Dr Nick Tiller from Harbor UCLA. Nick is a COPD and exercise researcher with other interests such as ultramarathon. However, the focus of this episode is on his expertise in regards to the importance of being skeptical of health and fitness claims. He has written the book A skeptics guide to sports science. He makes some very important points re critical thinking, conf
Integrative physiology of exercise with Dr Michael Joyner
Dr Glenn McConell chats with Professor Michael Joyner from the Mayo Clinic. He has a remarkable background being an anaesthesiologist with wealth of research experience and knowledge in exercise physiology. More recently he has published around 20 high impact papers on the use of convalescent plasma in Covid19! An example of how he is so open to new ideas. A very interesting chat. Twitter: @DrMJoy
Helping to start and maintain physical activity with Dr Stuart Biddle
Dr Glenn McConell chats with Professor Stuart Biddle who has a dual affiliation with the University of Southern Queensland (Australia) and the University of Jyvaskyla (Finland). A very interesting and informative chat with lots to think about. Stuart feels that we need to focus more on the environment than we have done, as well as the individual (particularly affect/feeling states/enjoyment)
Heat therapy, exercise and chronic disease with Dr Paige Geiger
Dr Glenn McConell chats with Professor Paige Geiger from the University of Kansas Medical Centre on Heat therapy, exercise and chronic disease. Paige has undertaken very important mechanistic and allied work in this field. We discussed many things (see time stamps below).
0:00. Introduction how got into the area
6:26. How first idea to look at heat and diabetes Phil Hooper in 1999 put
Exercise and type 2 diabetes with Dr John Hawley
Dr Glenn McConell chats with Professor John Hawley from the Australian Catholic University on Exercise and type 2 diabetes. John is one of the most recognized names in exercise metabolism. He has published over 300 journal articles (Google scholar: 40,000 citations, H index 113). We discussed many things (see time stamps below).
0:00. Introduction
1:34. Putting exercise and diet ahead of medic
Carbohydrate and protein requirements of endurance athletes with Dr Jørgen Jensen
Dr Glenn McConell chats with Professor Jørgen Jensen from the Norwegian School of Sport Sciences about Carbohydrate and protein requirements of endurance athletes. He has over 30 years of experience examining these areas. We focussed on muscle glycogen depletion during exercise and glycogen resynthesis after exercise. He thinks no mechanistic link between glycogen content and fatigue. Also discuss
Genetics and exercise in health and performance with Dr Claude Bouchard
Dr Glenn McConell chats with Professor Claude Bouchard about Genetics and exercise in health and performance. He recently retired at 82 yrs from the Louisiana State University Pennington Biomedical Research Center. He had made an amazing contribution with an H index of 191 and 173,000 citations!! (Google scholar).
0:00. Introduction
1:06. Got Covid19 then went flying fishing!&nb
Inactivity and exercise resistance and 4 second SIT training with Dr Eddie Coyle
Dr Glenn McConell chats with Professor Eddie Coyle from the University of Texas at Austin. Eddie has been instrumental in our understanding of the effects of carbohydrate ingestion and fluid ingestion during prolonged exercise and also physiological characteristics of endurance athletes (amongst other areas). Here we talk about his more recent very important and novel work.
0:00 Introduction
Women in science and female exercise physiology with Dr Abbie Smith-Ryan
Dr Glenn McConell talks with Professor Abbie Smith-Ryan from the University of North Carolina Chapel Hill about Women in science and female exercise physiology. Abbie has done remarkably well to publish 165 papers and be rapidly promoted to full Professor. Abbie talks about the challenges for women in science and also her research with female exercise physiology.
0:00. Introduction an
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